Our content on medicinal chemistry is limited but will be growing soon.
- medicinal chemistry overview (long with ~40 videos)
full range of topics relevant to medicinal chemistry – drug development & approval, pharmacodynamics, pharmacokinetics, lead discovery, & lead optimization - organic chemistry primer
octet rule, condensed structures, Lewis structures, functional groups, effects of polarity - introduction to drug discovery (non-science audience)
steps in drug discovery, proteins as drug targets, pharmacokinetics, metabolism, lead discovery, lead optimization - drug development process
unmet medical needs, steps in pre-clinical research, regulatory approval, generic drugs - target binding & phamacodynamics
target proteins, x-ray crystallography, enzyme inhibitors, receptor ligands, binding, efficacy, potency, off-target effects - drug metabolism & pharmacokinetics
Cp-time curves, exposure, area under curve, bioavailability, metabolism, clearance, volume of distribution, controlling half-life - lead discovery & lead optimization
molecular space, library screening, lead-like molecules, Lipinski’s rules, single point modification, off-target effects